19815 Bay Branch Rd
Andalusia, Alabama 36420
(334) 222-2523
HELPLINE: 1-877-530-0002



Facebook    

 

SCAMHC is an approved Mental Health site for the National Health Service Corps Loan Repayment program.  Find out the program details and see if you qualify by visiting: http://nhsc.hrsa.gov/

SCAMHC is an Equal Opportunity Provider and Employer and maintains a Drug-Free Workplace.

SCAMHC serves all individuals regardless of inability to pay. Discounts for essential services are offered based on family size and income. For more information, contact (334) 222-2523 or our 24/7 Helpline at 1-877-530-0002.

 

 


powered by centersite dot net
Alzheimers Disease and other Cognitive Disorders
Resources
Basic Information
Introduction & Causes of Cognitive DisordersDementiaAlzheimer's DiseaseOther Cognitive DisordersDementia Coping Skills & Behavior ManagementTraumatic Brain Injury (TBI)Conclusion and Resources
More InformationLatest News
Many Blacks, Hispanics Believe They'll Get Worse Care If Dementia StrikesAlzheimer's May Strike Women and Men in Different WaysHistory of Mental Illness Tied to Earlier Onset of Alzheimer's DiseaseAHA News: Black, Hispanic Families Hit Hardest by DementiaWhy Some 'Super Ager' Folks Keep Their Minds Dementia-FreeDementia Seen in Younger Adults Shows Even More Brain Damage Than Alzheimer'sToo Little Sleep Could Raise Your Dementia RiskSpecialist Care for Alzheimer's Is Tough to Find for Poorer, Rural AmericansTony Bennett's Struggle With Alzheimer's RevealedFluid-Filled Spaces in the Brain Linked to Worsening MemoryCOVID Vaccine Advised for Alzheimer's Patients, Their CaregiversAphasia Affects Brain Similar to Alzheimer's, But Without Memory LossCaregivers Feeling the Strain This Tough Holiday SeasonYears Before Diagnosis, People With Alzheimer's Lose Financial AcumenCould Dirty Air Help Speed Alzheimer's?Strong Sleeping Pills Tied to Falls, Fractures in Dementia PatientsAnxiety Might Speed Alzheimer's: StudyPre-Op 'Brain Games' Might Prevent Post-Op DeliriumDoes Hard Work Help Preserve the Brain?Staying Active as You Age Not a Guarantee Against DementiaSmog Tied to Raised Risk for Parkinson's, Alzheimer's DiseasePoor Brain Blood Flow Might Spur 'Tangles' of Alzheimer'sIs Apathy an Early Sign of Dementia?A-Fib Treatment Reduces Patients' Dementia RiskFall Risk Rises Even in Alzheimer's Early StagesPTSD May Be Tied to Greater Dementia RiskNew Research Links Another Gene to Alzheimer's RiskIs Rural Appalachia a Hotspot for Alzheimer's?Why Are Dementia Patients Getting Risky Psychiatric Drugs?Get Dizzy When Standing Up? It Could Be Risk Factor for DementiaCan Seniors Handle Results of Alzheimer's Risk Tests?More Education May Slow Start of Early-Onset Alzheimer'sUnder 50 and Overweight? Your Odds for Dementia Later May RiseBlood Test Heralds New Era in Alzheimer's Diagnosis9/11 First Responders Have Higher Odds for Alzheimer's: StudyCould the Flu Shot Lower Your Risk for Alzheimer's?Will Your Brain Stay Sharp Into Your 90s? Certain Factors Are KeyResearchers Zero in on Alzheimer's Disease Risk FactorsMany Americans With Dementia Live in Homes With GunsBrain's Iron Stores May Be Key to Alzheimer'sHormones May Explain Greater Prevalence of Alzheimer's in WomenMiddle-Age Obesity Linked to Higher Odds for DementiaCould Crohn's, Colitis Raise Dementia Risk?5 Healthy Steps to Lower Your Odds for Alzheimer'sCOVID-19 Brings New Challenges to Alzheimer's CaregivingAlzheimer's Gene Linked to Severe COVID-19 RiskHealthier Heart, Better Brain in Old AgeAHA News: Hearing Loss and the Connection to Alzheimer's Disease, DementiaBrain Plaques Signal Alzheimer's Even Before Other Symptoms Emerge: StudyCertain Gene Might Help Shield At-Risk People From Alzheimer's
Questions and AnswersVideosLinksBook Reviews
Related Topics

Aging & Geriatrics
Memory Problems
Elder Care

Will Your Brain Stay Sharp Into Your 90s? Certain Factors Are Key

HealthDay News
by By Steven Reinberg
HealthDay Reporter
Updated: Jul 22nd 2020

new article illustration

WEDNESDAY, July 22, 2020 (HealthDay News) -- Some people in their 90s stay sharp whether their brain harbors amyloid protein plaques -- a hallmark of Alzheimer's disease -- or not, but why?

That's the question researchers sought answers for among 100 people without dementia, average age 92, who were followed for up to 14 years. Their answer? A combination of genetic luck and a healthy, fulfilling lifestyle.

"The vast majority of research studies on aging and Alzheimer's disease try to understand what factors predict disease and memory impairment. We turned these questions upside-down, asking 'What seems to protect us from disease and impairment in our 90s?'" said lead researcher Beth Snitz, an associate professor of neurology at the University of Pittsburgh.

"Understanding this kind of resilience may well help identify ways to prevent dementia," Snitz added.

The study reinforces some things scientists already knew, such as the importance of good cardiovascular health and building up a "cognitive [mental] reserve. These likely can help buffer against the effects of brain disease or injury later in life," she said.

Her team also found that people whose scores were normal on thinking and memory tests when the study began were less likely to have problems with their thinking skills, even if they had amyloid protein plaques in their brains (which have been linked to Alzheimer's disease).

The researchers also found that those with the APOE2 gene mutation, which has been tied to a lower risk of Alzheimer's disease, were less likely to develop amyloid plaques than people who did not have this gene variant.

In fact, the APOE2 mutation was linked with a six times lower risk of developing plaques, the findings showed.

This mutation, however, is rare, occurring in only 10% of the people in the study. Among those with the mutation, 70% didn't develop plaques, the study authors noted.

Some lifestyle factors also affected brain aging. For example, those who never smoked were over 10 times more likely to keep their thinking skills, even with plaques, than smokers.

Also, high pulse pressure was linked with an increase in plaques. Pulse pressure is the systolic blood pressure (the top number in a blood pressure reading) minus the diastolic pressure (bottom number). Pulse pressure gets higher with age and is a sign of aging of the blood vessels.

The benefits of APOE2 alleles are well known, as is the link between smoking and poor cardiovascular health, said Dr. Sam Gandy, associate director of the Mount Sinai Alzheimer's Disease Research Center at the Icahn School of Medicine at Mount Sinai in New York City.

Also, the link between poor cardiovascular health and dementia is well-known.

"The pulse pressure story here has emerged lately, as has the apparent risk of overaggressive lowering of the blood pressure in chronic hypertensives [those with chronic high blood pressure], and an apparent association between dementia risk and erratic blood pressure," he said.

Other studies have found a benefit from exercise in preventing dementia, but this study didn't look at exercise, Snitz said. They also didn't look at the effect of maintaining an active social life or mental activities, such as reading, on preventing dementia, she said.

The investigators did find, however, that having a paying job in your 70s was protective against later memory decline.

"Other studies have shown that continuing to work -- or perhaps to keep one's mind engaged -- past conventional retirement age may be cognitively protective," Snitz said.

"We also found that 'life satisfaction' in the 70s was protective against later cognitive decline in the 80s and 90s," she added.

The report was published online July 22 in the journal Neurology.

Maria Corrada, a professor of epidemiology at the Institute for Memory Impairments and Neurological Disorders at the University of California, Irvine, said, "Some of the characteristics found to be related to resistance and resilience to Alzheimer's pathology can be changed or modified -- pulse pressure, smoking, paid work and life satisfaction."

Achieving these goals may be a way to be resistant or resilient to brain abnormalities associated with Alzheimer's disease, said Corrada, who co-authored an accompanying journal editorial.

"We believe that there are things we can do with our lifestyle that can help us maintain good cognitive health," she said.

More information

For more on dementia and Alzheimer's disease, head to the Alzheimer's Association.